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翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Molecular Interaction Maps ： ウィキペディア英語版 Molecular Interaction Maps Molecular Interaction Maps, also known as MIMs, is a graphic notation to depict cellular and molecular interactions. It was created by Kurt W. Kohn in 1999.〔Kohn KW. Molecular interaction map of the mammalian cell cycle control and DNA repair systems. (Mol Biol Cell (1999) )〕 The MIM convention is capable of unambiguous representation of networks containing multi-protein complexes, protein modifications, and enzymes that are substrates of other enzymes. This graphical representation makes it possible to view all of the many interactions in which a given molecule may be involved, and it can portray competing interactions, which are common in bioregulatory networks. In order to facilitate linkage to databases, each molecular species is represented only once in a diagram. The MIM notation forms the basis of, and further development of the MIM notation is coordinated with, the Systems Biology Graphical Notation (SBGN) consortium, an international effort to standardize diagrams depicting biochemical and cellular processes studied in systems biology. An update to the notation was published in 2006.〔Kohn KW, Aladjem MI, Weinstein JN, Pommier Y. Molecular interaction maps of bioregulatory networks: a general rubric for systems biology. (Mol Biol Cell (2006) ) 〕 ==Interpretation Modes== * Explicit: States exist only from interactions shown explicitly * Heuristic: Entities are treated as pools of states where states not explicitly shown may be possible * Combinatorial: Similar to heuristic, but all states are assumed to occur. The combinatorial interpretation of the MIM notation was described in a 2006 publication.〔Kohn KW, Aladjem MI, Kim S, Weinstein JN, Pommier Y. Depicting combinatorial complexity with the molecular interaction map notation. (Mol Syst Biol. 2006;2:51. (2006) ) 〕 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Molecular Interaction Maps」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.